Article
The role of TGFβ1 stimulating ROCK I signal pathway to reorganize actin in a rat experimental model of developmental dysplasia of the hip.
Molecular and cellular biochemistry - 1 Jun 2014
Pei Xinhong, Mo Yueqiang, Ning Bo, Yuan Zhe, Peng Luying, Ma Ruixue
Abstract excerpt
Importance of actin organization in control of chondrocyte phenotype is well established, but little is known about the role of transforming growth factor-β1 (TFGβ1) in regulating of ROCK I signal pathway. Here, we investigated the role of the TGFβ1, a well-studied member of the TGF-β superfamily, in chondrogenesis. Newborn Rats were randomly assigned to developmental dysplasia of the hip (DDH) group and control...
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