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Article

Rho Kinases in Health and Disease: From Basic Science to Translational Research.

Pharmacological reviews - 1 Oct 2015

Loirand Gervaise

Abstract excerpt

Rho-associated kinases ROCK1 and ROCK2 are key regulators of actin cytoskeleton dynamics downstream of Rho GTPases that participate in the control of important physiologic functions, S including cell contraction, migration, proliferation, adhesion, and inflammation. Several excellent review articles dealing with ROCK function and regulation have been published over the past few years. Although a brief overview of...

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Source

Identifiers

PMID: 26419448
DOI: 10.1124/pr.115.010595

Genes

ROCK1
ROCK2

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