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Article

Chondrocyte suppression is mediated by miR‐129‐5p via GDF11/SMAD3 signaling in developmental dysplasia of the hip

12 May 2020

Abstract excerpt

Recent studies have shown that developmental dysplasia of the hip (DDH) during childhood and in animal models is associated with impaired endochondral ossification of the roof of the acetabulum, yet the molecular mechanism of this pathology remains unknown. To address this, an animal model of DDH was established in 4-week-old New Zealand white rabbits by cast immobilization of knee extension. Fifty-six rabbits of...

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PMID: 32396235
DOI: 10.1002/jor.24713

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