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Article

Interaction of TGFβ and BMP Signaling Pathways during Chondrogenesis

28 Jan 2011

Abstract excerpt

TGFβ and BMP signaling pathways exhibit antagonistic activities during the development of many tissues. Although the crosstalk between BMP and TGFβ signaling pathways is well established in bone development, the relationship between these two pathways is less well defined during cartilage development and postnatal homeostasis. We generated hypomorphic mouse models of cartilage-specific loss of BMP and TGFβ...

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PMID: 21297990
DOI: 10.1371/journal.pone.0016421

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