Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton

1 Jan 2018

Abstract excerpt

TGFβis a potent regulator of several biological functions in many cell types, but its role in the differentiation of human bone marrow-derived skeletal stem cells (hMSCs) is currently poorly understood. In the present study, we demonstrate that a single dose of TGFβ1 prior to induction of osteogenic or adipogenic differentiation results in increased mineralized matrix or increased numbers of lipid-filled mature...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules Research
Share to Cellular Mechanics and Interactions
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29535777
DOI: 10.1155/2018/6913594

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin CytoskeletonPMID 29535777Read ↗

SERPINB2 is a novel TGFβ-responsive lineage fate determinant of human bone marrow stromal cells.Semantic proximity Read ↗

TGFβ1 contributes to cardiomyogenic-like differentiation of human bone marrow mesenchymal stem cellsSemantic proximity Read ↗

Transgelin is a TGFβ-inducible gene that regulates osteoblastic and adipogenic differentiation of human skeletal stem cells through actin cytoskeleston organizationSemantic proximity Read ↗

Cooperation Between TGF-β and Wnt Pathways During Chondrocyte and Adipocyte Differentiation of Human Marrow Stromal CellsSemantic proximity Read ↗

Convergence of TGFβ and BMP signaling in regulating human bone marrow stromal cell differentiationSemantic proximity Read ↗

TGFβ/BMP Signaling Pathway in Cartilage HomeostasisSemantic proximity Read ↗

Cytoskeletal signaling in <scp>TGF</scp>β‐induced epithelial–mesenchymal transitionSemantic proximity Read ↗

PDGF, TGF-β, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in differentiation of MSCs into adipogenic, chondrogenic, and osteogenic lineagesSemantic proximity Read ↗

TGFβ signaling and the control of myofibroblast differentiation: Implications for chronic inflammatory disorders.Semantic proximity Read ↗

Gene expression profiling of TGFβ2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-β2 signalingSemantic proximity Read ↗

Collagen Modulates the Biological Characteristics of WJ-MSCs in Basal and Osteoinduced ConditionsSemantic proximity Read ↗

TGF-β signaling regulates differentiation of MSCs in bone metabolism: disputes among viewpointsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.