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Article

The human squamous oesophagus has widespread capacity for clonal expansion from cells at diverse stages of differentiation

26 Feb 2014

Abstract excerpt

OBJECTIVE: Knowledge of the cellular mechanisms involved in homeostasis of human squamous oesophagus in the steady state and following chronic injury is limited. We aimed to better understand these mechanisms by using a functional 3D approach. DESIGN: Proliferation, mitosis and the expression of progenitor lineage markers were assessed in normal squamous oesophagus from 10 patients by immunofluorescence on 3D...

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PMID: 24572143
DOI: 10.1136/gutjnl-2013-306171

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