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Article

Single-cell analysis defines the lineage plasticity of stem cells in cervix epithelium

31 Oct 2021

Abstract excerpt

Information about the dynamic change and post-injury regeneration of cervical epithelium is relatively rare, even though it is tightly related to gynecologic malignancy. Here, using a feeder cell-based culturing system, we stably cloned mouse and human P63 and KRT5 expressing cells from the adult cervix as putative cervical stem/progenitor cells (CVSCs). When subjected to differentiation, the cultured cells gave...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34719766
DOI: 10.1186/s13619-021-00096-2

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