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Quantification of epithelial cell proliferation, cell dynamics, and cell kinetics in vivo

5 May 2017

Abstract excerpt

The measurement of cell proliferation in vivo is usually carried out by the examination of static measures. These comprise the mitotic index or labeling indices using incorporation of DNA synthesis markers such as bromodeoxyuridine or tritiated thymidine, or intrinsic markers, such as Ki67 and proliferative cell nuclear antigen (PCNA). But static measures only provide a 'snapshot' of cell proliferation. Rate...

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PMID: 28474479
DOI: 10.1002/wdev.274

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