Article

Modeling epithelial homeostasis and perturbation in three-dimensional human esophageal organoids

2024-05-21

Abstract excerpt

<h4>Background</h4> Esophageal organoids from a variety of pathologies including cancer are grown in Advanced Dulbecco’s Modified Eagle Medium-Nutrient Mixture F12 (hereafter ADF). However, the currently available ADF-based formulations are suboptimal for normal human esophageal organoids, limiting the ability to compare normal esophageal organoids with those representing a given disease state. <h4>Methods</h4>...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1deeca10-9c1a-539d-806e-f9ec3775bbb3
DOI: 10.1101/2024.05.20.595023

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Modeling epithelial homeostasis and perturbation in three-dimensional human esophageal organoidsDOI 10.1101/2024.05.20.595023Read

Understanding the cellular origin and progression of esophageal cancer using esophageal organoids.Semantic proximity Read

<i>In vitro</i> models of the human esophagus reveal ancestrally diverse response to injurySemantic proximity Read

In Vitro Model for Studying Esophageal Epithelial Differentiation and Allergic Inflammatory Responses Identifies Keratin Involvement in Eosinophilic EsophagitisSemantic proximity Read

Suspension-Based Human Esophagoids Recapitulate WNT2B-Dependent Regulation of Esophageal Basal ProgenitorsSemantic proximity Read

Lysyl oxidase regulates epithelial differentiation and barrier integrity in eosinophilic esophagitisSemantic proximity Read

Development of novel <i>in vitro</i> human alveolar epithelial cell models to study distal lung biology and diseaseSemantic proximity Read

Developments in gastrointestinal organoid cultures to recapitulate tissue environmentsSemantic proximity Read

Modeling inflammation and oxidative stress in gastrointestinal disease development using novel organotypic culture systemsSemantic proximity Read

Molecular and Functional Characterization of Human Intestinal Organoids and Monolayers for Modeling Epithelial BarrierSemantic proximity Read

Interferon-γ signaling in eosinophilic esophagitis has implications for epithelial barrier function and programmed cell deathSemantic proximity Read

Eosinophilic esophagitis-associated epithelial remodeling may limit esophageal carcinogenesisSemantic proximity Read

Development and Characterization of In Vitro Human Oral Mucosal Equivalents Derived from Immortalized Oral KeratinocytesSemantic proximity Read