Article
CUBN and NEBL common variants in the chromosome 10p13 linkage region are associated with multibacillary leprosy in Vietnam.
Human genetics - 1 Jul 2014
Grant Audrey V, Cobat Aurelie, Van Thuc Nguyen, Orlova Marianna, Huong Nguyen Thu, Gaschignard Jean, Alter Andrea, Ba Nguyen Ngoc, Thai Vu Hong, Abel Laurent, Alcaïs Alexandre, Schurr Erwin
Abstract excerpt
Leprosy is caused by infection with Mycobacterium leprae and is classified clinically into paucibacillary (PB) or multibacillary (MB) subtypes based on the number of skin lesions and the bacillary index detected in skin smears. We previously identified a major PB susceptibility locus on chromosome region 10p13 in Vietnamese families by linkage analysis. In the current study, we conducted high-density association...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
