Article
Mapping of PARK2 and PACRG overlapping regulatory region reveals LD structure and functional variants in association with leprosy in unrelated indian population groups.
PLoS genetics - 1 Jan 2013
Chopra Rupali, Ali Shafat, Srivastava Amit K, Aggarwal Shweta, Kumar Bhupender, Manvati Siddharth, Kalaiarasan Ponnusamy, Jena Mamta, Garg Vijay K, Bhattacharya Sambit N, Bamezai Rameshwar N K
Abstract excerpt
Leprosy is a chronic infectious disease caused by Mycobacterium Leprae, where the host genetic background plays an important role toward the disease pathogenesis. Various studies have identified a number of human genes in association with leprosy or its clinical forms. However, non-replication of results has hinted at the heterogeneity among associations between different population groups, which could be due to...
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