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Article

Common variants of OPA1 conferring genetic susceptibility to leprosy in Han Chinese from Southwest China.

Journal of dermatological science - 1 Nov 2015

Xiang Yang-Lin, Zhang Deng-Feng, Wang Dong, Li Yu-Ye, Yao Yong-Gang

Abstract excerpt

BACKGROUND: Leprosy is an ancient chronic infection caused by Mycobacterium leprae. Onset of leprosy was highly affected by host nutritional condition and energy production, (partially) due to genomic loss and parasitic life style of M. leprae. The optic atrophy 1 (OPA1) gene plays an essential role in mitochondria, which function in cellular energy supply and innate immunity. OBJECTIVE: To investigate the...

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Source

Identifiers

PMID: 26360011
DOI: 10.1016/j.jdermsci.2015.09.001

Genes

OPA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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