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Article

No evidence that runs of homozygosity are associated with schizophrenia in an Irish genome-wide association dataset.

Schizophrenia research - 1 Apr 2014

Heron Elizabeth A, Cormican Paul, Donohoe Gary, O'Neill Francis A, Kendler Kenneth S, Riley Brien P, Gill Michael, Corvin Aiden P, Morris Derek W

Abstract excerpt

Runs of homozygosity (ROH), regions of the genome containing many consecutive homozygous SNPs, may represent two copies of a haplotype inherited from a common ancestor. A rare variant on this haplotype could thus be present in a homozygous and potentially recessive state. To detect rare risk variants for schizophrenia, we performed an ROH analysis in a homogeneous Irish genome wide association study (GWAS)...

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Identifiers

PMID: 24560374
DOI: 10.1016/j.schres.2014.01.038
PMCID: PMC4034753

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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