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Article

Genome-wide analysis of runs of homozygosity in Pakistani controls with no history of speech or language-related developmental phenotypes.

Annals of human biology - 1 Feb 2023

Yasmin Tahira, Andres Erin M, Ashraf Komal, Basra Muhammad Asim Raza, Raza Muhammad Hashim

Abstract excerpt

BACKGROUND: Runs of homozygosity (ROHs) analysis of controls provide a convenient resource to minimize the association of false positive results of disease-associated ROHs and genetic variants for simple and complex disorders in individuals from the same population. Evidence for the value of ROHs to speech or language-related traits is restricted due to the absence of population-matched behaviourally defined...

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Identifiers

PMID: 36786444
DOI: 10.1080/03014460.2023.2180087
PMCID: PMC10284496

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