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Regions of homozygosity and their impact on complex diseases and traits.

Human genetics - 1 Jan 2011

Ku Chee Seng, Naidoo Nasheen, Teo Shu Mei, Pawitan Yudi

Abstract excerpt

Regions of homozygosity (ROHs) are more abundant in the human genome than previously thought. These regions are without heterozygosity, i.e. all the genetic variations within the regions have two identical alleles. At present there are no standardized criteria for defining the ROHs resulting in the different studies using their own criteria in the analysis of homozygosity. Compared to the era of genotyping...

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PMID: 21104274
DOI: 10.1007/s00439-010-0920-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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