Article
Genetic analysis of BMP4 gene in Chinese Han female population with premature ovarian insufficiency.
Climacteric : the journal of the International Menopause Society - 1 Jun 2014
Bai T, Yang J, Chen B, Wang B, Ma X, Cao Y
Abstract excerpt
The bone morphogenetic protein 4 (BMP4) gene is related to development of female reproductive organs in animal models. However, to date, there has been no consensus on the relationship between mutations in BMP4 and premature ovarian insufficiency (POI) in human beings. To analyze variations in BMP4 in Chinese women with POI, we sequenced two coding regions of BMP4 in 99 Han Chinese women with POI after DNA...
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