Article
Association between TGF-β/BMP signaling pathway polymorphisms and the risk of primary ovarian insufficiency in Korean women.
Genes & genomics - 1 Oct 2024
Ha Yong Hyun, Kim Ji Hyang, Ryu Chang Soo, Kim Ji Won, Ko Eun Ju, Lee Jeong Yong, Shin Ji Eun, Kim Young Ran, Ahn Eun Hee, Kim Nam Keun
Abstract excerpt
BACKGROUND: Primary ovarian insufficiency (POI) is one of the leading female infertility diseases in which ovarian function stops before the age of 40. Reports that POI is associated with transforming growth factor (TGF)-β/bone morphogenetic protein (BMP) signaling pathway-associated genes (e.g., TGF-β, and BMP15) have been continuous since publication that the TGF-β superfamily acts as important regulators for...
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