Article
"Evaluation of four genes associated with primary ovarian insufficiency in a cohort of Mexican women".
Journal of assisted reproduction and genetics - 1 Aug 2018
Juárez-Rendón K J, García-Ortiz J E
Abstract excerpt
PURPOSE: Primary ovarian insufficiency (POI) is a clinical condition observed in women younger than 40 years of age, characterized by amenorrhea, hypoestrogenism, high levels of follicle-stimulating hormone (FSH), and infertility. Mutations in some master regulators of the development, maturation, and maintenance of ovarian follicles such as BMP15, FSHR, FOXL2, and GDF9 have been suggested as etiological factors...
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