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Article

Analysis of progesterone receptor membrane component 1 mutation in Han Chinese women with premature ovarian failure.

Reproductive biomedicine online - 1 Nov 2014

Wang Jiu-Ling, Li Shu-Ling, Qin Ying-Ying, Chen Zi-Jiang

Abstract excerpt

The gene PGRMC1 is highly expressed in the granulose and luteal cells of rodent and primate ovaries. Its role in anti-apoptosis and regulating cell-cycle progression suggests a role in regulating follicle growth. The hypothesis is supported by the study in mice and studies in Sweden. In this study, the coding exons of PGRMC1 were sequenced among 196 Chinese women with premature ovarian failure (POF) and 200...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25246111
DOI: 10.1016/j.rbmo.2014.08.001

Genes

PGRMC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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