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Article

Genome-wide association study and premature ovarian failure.

Annales d'endocrinologie - 1 May 2010

Christin-Maitre S, Tachdjian G

Abstract excerpt

Premature ovarian failure (POF) is defined as an amenorrhea for more than 4months, associated with elevated gonadotropins, usually higher than 20mIU/ml, occurring in a woman before the age of 40. Some candidate genes have been identified in the past 15years, such as FOXL2, FSHR, BMP15, GDF9, Xfra premutation. However, POF etiology remains unknown in more than 90% of cases. The first strategy to identify candidate...

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Source

Identifiers

PMID: 20362963
DOI: 10.1016/j.ando.2010.02.014

Genes

ADAMTS19
BMP15
FOXL2
FSHR
GDF9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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