Article
Single nucleotide polymorphisms in premature ovarian failure-associated genes in a Chinese Hui population.
Molecular medicine reports - 1 Aug 2015
Ma Lili, Chen Yan, Mei Si, Liu Chunlian, Ma Xiaohong, Li Yongli, Jiang Yinzhi, Ha Lingxia, Xu Xian
Abstract excerpt
Premature ovarian failure (POF) is an ovarian defect characterized by the premature depletion of ovarian follicles in individuals <40 years old, and is a major cause of infertility in females. Genetic factors are considered to be responsible for the development of POF, however, the exact pathogenesis remains to be elucidated in the majority of cases. In the present study, the single nucleotide polymorphisms...
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