Article
Sequence variants in exons of the BMP-15 gene in Chinese patients with premature ovarian failure.
Acta obstetricia et gynecologica Scandinavica - 1 Jan 2007
Zhang Peng, Shi Yu-Hua, Wang Lai-Cheng, Chen Zi-Jiang
Abstract excerpt
BACKGROUND: The bone morphogenetic protein-15 (BMP-15) gene is thought to be one of the important candidate genes involved in premature ovarian failure (POF). However, to date, there has been no consensus on the relationship between mutations in BMP-15 and ovarian dysfunction. OBJECTIVE: To analyse mutations in the BMP-15 gene in Chinese women with POF. MATERIALS AND METHODS: We sequenced the BMP-15 gene protein...
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