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Article

BMPR1A and BMPR1B Missense Mutations Cause Primary Ovarian Insufficiency.

The Journal of clinical endocrinology and metabolism - 1 Apr 2020

Renault Lucie, Patiño Liliana C, Magnin Françoise, Delemer Brigitte, Young Jacques, Laissue Paul, Binart Nadine, Beau Isabelle

Abstract excerpt

CONTEXT: Primary ovarian insufficiency (POI) is a frequently occurring disorder affecting approximately 1% of women under 40 years of age. POI, which is characterized by the premature depletion of ovarian follicles and elevated plasma levels of follicle-stimulating hormone, leads to infertility. Although various etiological factors have been described, including chromosomal abnormalities and gene mutations, most...

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Identifiers

PMID: 31769494
DOI: 10.1210/clinem/dgz226

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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