In silico discovery of gene-coding variants in murine quantitative trait loci using strain-specific genome sequence databases.

doi:10.1186/gb-2002-3-12-research0078

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Article

In silico discovery of gene-coding variants in murine quantitative trait loci using strain-specific genome sequence databases.

Genome biology - 1 Jan 2002

Marshall Kriste E, Godden Elizabeth L, Yang Fan, Burgers Sonya, Buck Kari J, Sikela James M

Abstract excerpt

BACKGROUND: The identification of genes underlying complex traits has been aided by quantitative trait locus (QTL) mapping approaches, which in turn have benefited from advances in mammalian genome research. Most recently, whole-genome draft sequences and assemblies have been generated for mouse strains that have been used for a large fraction of QTL mapping studies. Here we show how such strain-specific mouse...

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Identifiers

PMID: 12537567
DOI: 10.1186/gb-2002-3-12-research0078
PMCID: PMC151180

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.