Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic copy number and expression variation within the C57BL/6J inbred mouse strain.

Genome research - 1 Jan 2008

Watkins-Chow Dawn E, Pavan William J

Abstract excerpt

The C57BL/6J strain is one of the most widely used animal models for biomedical research, and individual mice within the strain are often assumed to be genetically identical after more than 70 yr of inbreeding. Using a single nucleotide polymorphism (SNP) genotyping panel, we assessed if copy number variations (CNVs) could be detected within the C57BL/6J strain by comparing relative allele frequencies in first...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes
Share to Gene Dosage
Share to Genome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulysin

Share to Mice, Inbred Strains

Share to Nucleic Acid Hybridization

Share to Receptor, Fibroblast Growth Factor, Type 3

Share to Species Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 18032724
DOI: 10.1101/gr.6927808
PMCID: PMC2134784

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic copy number and expression variation within the C57BL/6J inbred mouse strain.PMID 18032724Read ↗

Polymorphic SNPs, short tandem repeats and structural variants are responsible for differential gene expression across C57BL/6 and C57BL/10 substrainsSemantic proximity Read ↗

Significant gene content variation characterizes the genomes of inbred mouse strains.Semantic proximity Read ↗

A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.Semantic proximity Read ↗

Whole-genome sequence of the C57L/J mouse inbred strain.Semantic proximity Read ↗

Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation, and homozygous truncating mutationsSemantic proximity Read ↗

Deep genome sequencing and variation analysis of 13 inbred mouse strains defines candidate phenotypic alleles, private variation and homozygous truncating mutations.Semantic proximity Read ↗

High-Resolution Maps of Mouse Reference Populations.Semantic proximity Read ↗

High throughput sequencing in mice: a platform comparison identifies a preponderance of cryptic SNPs.Semantic proximity Read ↗

Alcohol trait and transcriptional genomic analysis of C57BL/6 substrains.Semantic proximity Read ↗

Complex haplotypes, copy number polymorphisms and coding variation in two recently divergent mouse strains.Semantic proximity Read ↗

Into the Wild: A novel wild-derived inbred strain resource expands the genomic and phenotypic diversity of laboratory mouse models.Semantic proximity Read ↗

Genetic polymorphisms among C57BL/6 mouse inbred strains.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.