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Article

Copy number variant detection in inbred strains from short read sequence data.

Bioinformatics (Oxford, England) - 15 Feb 2010

Simpson Jared T, McIntyre Rebecca E, Adams David J, Durbin Richard

Abstract excerpt

SUMMARY: We have developed an algorithm to detect copy number variants (CNVs) in homozygous organisms, such as inbred laboratory strains of mice, from short read sequence data. Our novel approach exploits the fact that inbred mice are homozygous at virtually every position in the genome to detect...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20022973
DOI: 10.1093/bioinformatics/btp693
PMCID: PMC2820678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20022973-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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