Article
Impact of comorbid hepatic steatosis on treatment of chronic hepatitis C in Japanese patients and the relationship with genetic polymorphism of IL28B, PNPLA3 and LDL receptor.
Acta medica Okayama - 1 Jan 2014
Moritou Yuki, Ikeda Fusao, Iwasaki Yoshiaki, Baba Nobuyuki, Takaguchi Kouichi, Senoh Tomonori, Nagano Takuya, Takeuchi Yasuto, Yasunaka Tetsuya, Ohnishi Hideki, Miyake Yasuhiro, Takaki Akinobu, Nouso Kazuhiro, Yamamoto Kazuhide
Abstract excerpt
The impact of hepatic steatosis on interferon therapy for patients with chronic hepatitis C (CHC) has been associated with single-nucleotide polymorphisms (SNP) of IL28B, patatin-like phospholipase domain-containing protein 3 (PNPLA3), and low-density lipoprotein (LDL) receptor. Whether this holds true for Japanese patients, however, remains unresolved. The present study prospectively enrolled 226 Japanese...
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