Possible Relevance of PNPLA3 and TLL1 Gene Polymorphisms to the Efficacy of PEG-IFN Therapy for HBV-Infected Patients.

doi:10.3390/ijms21093089

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Article

Possible Relevance of PNPLA3 and TLL1 Gene Polymorphisms to the Efficacy of PEG-IFN Therapy for HBV-Infected Patients.

International journal of molecular sciences - 27 Apr 2020

Enomoto Hirayuki, Aizawa Nobuhiro, Hasegawa Kunihiro, Ikeda Naoto, Sakai Yoshiyuki, Yoh Kazunori, Takata Ryo, Yuri Yukihisa, Kishino Kyohei, Shimono Yoshihiro, Ishii Noriko, Takashima Tomoyuki, Nishimura Takashi, Nishikawa Hiroki, Iwata Yoshinori, Iijima Hiroko, Nishiguchi Shuhei

Abstract excerpt

Lifestyle changes have led to an increase in the number of patients with nonalcoholic fatty liver disease (NAFLD). However, the effects of NAFLD-associated single-nucleotide gene polymorphisms (SNPs) in HBV-infected patients have not been adequately investigated. Methods: We investigated the association of the NAFLD-related SNPs patatin-like phospholipase domain-containing protein 3 (PNPLA3; rs738409),...

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PMID: 32349377
DOI: 10.3390/ijms21093089
PMCID: PMC7247697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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