Article
No correlation between PNPLA3 rs738409 genotype and fatty liver and hepatic cirrhosis in Japanese patients with HCV.
PloS one - 1 Jan 2013
Nakamura Masato, Kanda Tatsuo, Nakamoto Shingo, Miyamura Tatsuo, Jiang Xia, Wu Shuang, Yokosuka Osamu
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) infection is associated with the development of cirrhosis and hepatocellular carcinoma and is also related to fatty change of the liver. Variation in patatin-like phospholipase domain-containing 3 (PNPLA3) gene is associated with disease progression in nonalcoholic fatty liver disease (NAFLD). Recent reports have suggested that PNPLA3, IL28B and TLR4-associated single...
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