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Article

Involvement of Telomerase Reverse Transcriptase in Heterochromatin Maintenance

19 Feb 2014

Abstract excerpt

In the fission yeast Schizosaccharomyces pombe, centromeric heterochromatin is maintained by an RNA-directed RNA polymerase complex (RDRC) and the RNA-induced transcriptional silencing (RITS) complex in a manner that depends on the generation of short interfering RNA. In association with the telomerase RNA component (TERC), the telomerase reverse transcriptase (TERT) forms telomerase and counteracts telomere...

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Share to Chromosomal and Genetic Variations
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PMID: 24550003
DOI: 10.1128/mcb.00093-14

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