Article
Role of heterochromatin in suppressing subtelomeric recombination in fission yeast.
Yeast (Chichester, England) - 1 Aug 2008
Bisht Kamlesh Kumar, Arora Sumit, Ahmed Shakil, Singh Jagmohan
Abstract excerpt
Telomere length is regulated by a complex interplay of several factors, including telomerase, telomere-binding proteins, DNA replication machinery and recombination. In yeast, DNA polymerase alpha is required for de novo synthesis of telomeres from broken ends of DNA, and it also suppresses the elongation of normal telomeric repeats. Heterochromatin proteins Clr1-Clr4 and Swi6 and DNA polalpha organize...
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