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Article

Dietary iron, iron homeostatic gene polymorphisms and the risk of advanced colorectal adenoma and cancer.

Carcinogenesis - 1 Jun 2014

Ruder Elizabeth H, Berndt Sonja I, Gilsing Anne M J, Graubard Barry I, Burdett Laurie, Hayes Richard B, Weissfeld Joel L, Ferrucci Leah M, Sinha Rashmi, Cross Amanda J

Abstract excerpt

Dietary iron intake and variation in iron homeostasis genes may affect colorectal neoplasia risk. We conducted two nested case-control studies within the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial: one of advanced colorectal adenoma (1205 cases; 1387 controls) and one of colorectal cancer (370 cases; 401 controls). Iron intake was estimated with a food frequency questionnaire and genotyping was...

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Identifiers

PMID: 24536049
DOI: 10.1093/carcin/bgu028
PMCID: PMC4043236

Genes

ACO1
HEPHL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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