Article
Dietary Iron and Heme Iron Consumption, Genetic Susceptibility, and Risk of Crohn's Disease and Ulcerative Colitis.
Inflammatory bowel diseases - 1 Jul 2017
Khalili Hamed, de Silva Punyanganie S, Ananthakrishnan Ashwin N, Lochhead Paul, Joshi Amit, Garber John J, Richter James R, Sauk Jenny, Chan Andrew T
Abstract excerpt
BACKGROUND: Dietary iron and heme, likely through their effect on gut commensal bacteria and colonic barrier function, have been shown to modulate colonic inflammation in animal models of colitis. Nonetheless, the link between dietary total and heme iron and risk of Crohn's disease (CD) and ulcerative colitis (UC) has not been previously explored. METHODS: We conducted a prospective cohort study of 165,331 U.S....
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