Article
Association of polymorphisms of calcium reabsorption genes SLC12A1, KCNJ1 and SLC8A1 with colorectal adenoma.
Journal of cancer research and clinical oncology - 1 Sept 2023
Lai Xiaolian, Lu Shuoyan, Jiang Jia, Zhang Hanqun, Yang Qinglin, Liu Yuncong, Li Libo, Li Sanming, Dai Si, Chen Yanping, Chen Yan, Liu Jun, Li Yong
Abstract excerpt
BACKGROUND: In recent years, morbidity and mortality from colorectal cancer have increased. Colorectal adenoma is the main precancerous lesion. Understanding the pathogenesis of colorectal adenoma will help to improve the early diagnosis rate of colorectal cancer. METHODS: In this case-control study, we focused on three single nucleotide polymorphisms (SNPs) in genes SLC8A1 (rs4952490), KCNJ1 (rs2855798), and...
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