Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Iron biomarkers in plasma, HFE genotypes, and the risk for colorectal cancer in a prospective setting.

Diseases of the colon and rectum - 1 Mar 2012

Ekblom Kim, Marklund Stefan L, Palmqvist Richard, Van Guelpen Bethany, Hallmans Göran, Weinehall Lars, Hultdin Johan

Abstract excerpt

BACKGROUND: High iron levels can increase the formation of noxious oxygen radicals, which are thought to promote carcinogenesis. OBJECTIVE: The aim of this prospective study was to determine whether iron biomarkers and HFE genotypes, which influence iron regulation, constitute risk factors for colorectal cancer. DESIGN: This is a prospective nested case-referent study. SETTINGS: The study was performed within the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ferritins

Share to Hemochromatosis Protein

Share to Histocompatibility Antigens Class I

Share to Membrane Proteins

Share to Transferrin

Source

Identifiers

PMID: 22469802
DOI: 10.1097/DCR.0b013e318241199e

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Iron biomarkers in plasma, HFE genotypes, and the risk for colorectal cancer in a prospective setting.PMID 22469802Read ↗

Hemochromatosis gene mutations, body iron stores, dietary iron, and risk of colorectal adenoma in women.Semantic proximity Read ↗

Gender and plasma iron biomarkers, but not HFE gene mutations, increase the risk of colorectal cancer and polyps.Semantic proximity Read ↗

Premenopausal plasma ferritin levels, HFE polymorphisms, and risk of breast cancer in the nurses' health study II.Semantic proximity Read ↗

Plasma ferritin levels, HFE polymorphisms, and risk of pancreatic cancer among Chinese Han population.Semantic proximity Read ↗

Association between hemochromatosis (HFE) gene mutation carrier status and the risk of colon cancer.Semantic proximity Read ↗

Health Implications of Iron Overload: the Role of Diet and GenotypeSemantic proximity Read ↗

HFE variants in colorectal cancer and their clinicopathological correlations.Semantic proximity Read ↗

Liver iron levels are associated with HFE-hemochromatosis genotype, diet, adiposity, and disease in the UK Biobank.Semantic proximity Read ↗

Dietary iron, iron homeostatic gene polymorphisms and the risk of advanced colorectal adenoma and cancer.Semantic proximity Read ↗

Diet and genetic factors associated with iron status in middle-aged women.Semantic proximity Read ↗

Iron homeostasis and distal colorectal adenoma risk in the prostate, lung, colorectal, and ovarian cancer screening trial.Semantic proximity Read ↗

Liver iron levels are associated with<i>HFE</i>-hemochromatosis genotype, diet, adiposity, and disease in the UK BiobankSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.