Article
Hemochromatosis gene mutations and distal adenomatous colorectal polyps.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2005
McGlynn Katherine A, Sakoda Lori C, Hu Ying, Schoen Robert E, Bresalier Robert S, Yeager Meredith, Chanock Stephen, Hayes Richard B, Buetow Kenneth H
Abstract excerpt
Iron has been suggested to be a risk factor for colorectal neoplasia. Some individuals who are heterozygous for mutations in the hemochromatosis gene (HFE) have higher than average serologic measures of iron. We therefore investigated whether heterozygosity for HFE mutations was related to risk of advanced distal adenoma and whether the relationship was affected by dietary iron intake. In the Prostate, Lung,...
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