Article
Iron homeostasis and distal colorectal adenoma risk in the prostate, lung, colorectal, and ovarian cancer screening trial.
Cancer prevention research (Philadelphia, Pa.) - 1 Sept 2011
Cross Amanda J, Sinha Rashmi, Wood Richard J, Xue Xiaonan, Huang Wen-Yi, Yeager Meredith, Hayes Richard B, Gunter Marc J
Abstract excerpt
Red meat consumption has been positively associated with colorectal cancer; however, the biological mechanism underlying this relationship is not understood. Red meat is a major source of iron, which may play a role in colorectal carcinogenesis via increased crypt cell proliferation, cytotoxicity, and endogenous N-nitrosation. In a nested case-control study within the Prostate, Lung, Colorectal, and Ovarian...
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