Article
Diet-Wide Association, Genetic Susceptibility and Colorectal Cancer Risk: A Prospective Cohort Study.
Nutrients - 16 Nov 2023
Jin Dongqing, Lu Ying, Wu Wei, Jiang Fangyuan, Li Zihan, Xu Liying, Zhang Rongqi, Li Xue, Chen Dong
Abstract excerpt
BACKGROUND: Both genetic and dietary factors play significant roles in the etiology of colorectal cancer (CRC). To evaluate the relationship between certain food exposures and the risk of CRC, we carried out a large-scale association analysis in the UK Biobank. METHODS: The associations of 139 foods and nutrients' intake with CRC risk were assessed among 118,210 participants. A polygenic risk score (PRS) of CRC...
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