Article
Genetic diversity of Merozoite surface protein 1-42 (MSP1-42) fragment of Plasmodium vivax from Indonesian isolates: Rationale implementation of candidate MSP1 vaccine.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Nov 2020
Murhandarwati E Elsa Herdiana, Herningtyas E Henny, Puspawati Puspawati, Mau Fridolina, Chen Shen-Bo, Shen Hai-Mo, Chen Jun-Hu
Abstract excerpt
Morbidity and mortality related to malaria in Indonesia are attributed to both Plasmodium falciparum and P. vivax parasites. In addition to vaccines for P. falciparum, vaccines against P. vivax are urgently needed for the prevention of the disease. An extensively studied antigen is the carboxyl-terminus of the 42 kDa region of P. vivax merozoite surface protein-1 (PvMSP1-42). The design of a vaccine based on this...
Topics
- Alleles
- Antigens, Protozoan
- Genetic Variation
- Humans
- Indonesia
- Malaria Vaccines
- Malaria, Vivax
- Merozoite Surface Protein 1
- Models, Molecular