Article
Does disruption of circadian rhythms contribute to beta-cell failure in type 2 diabetes?
Current diabetes reports - 1 Apr 2014
Rakshit Kuntol, Thomas Anthony P, Matveyenko Aleksey V
Abstract excerpt
Type 2 diabetes mellitus (T2DM) is a complex metabolic disease characterized by the loss of beta-cell secretory function and mass. The pathophysiology of beta-cell failure in T2DM involves a complex interaction between genetic susceptibilities and environmental risk factors. One environmental condition that is gaining greater appreciation as a risk factor for T2DM is the disruption of circadian rhythms (eg,...
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