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Article

Clock genes in pancreatic disease progression: from circadian regulation to dysfunction

13 Jul 2025

Abstract excerpt

BACKGROUND: Circadian rhythms, governed by core clock genes, are essential for maintaining metabolic, endocrine, and immune homeostasis. Disruption of these rhythms has been increasingly implicated in the pathogenesis of various pancreatic diseases. OBJECTIVE: This review summarizes current evidence on the role of circadian rhythm disruption in pancreatic diseases, including type 2 diabetes (T2D), type 1 diabetes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40652400
DOI: 10.1080/07853890.2025.2528449

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