Article
Circadian clocks and metabolism.
Handbook of experimental pharmacology - 1 Jan 2013
Marcheva Biliana, Ramsey Kathryn M, Peek Clara B, Affinati Alison, Maury Eleonore, Bass Joseph
Abstract excerpt
Circadian clocks maintain periodicity in internal cycles of behavior, physiology, and metabolism, enabling organisms to anticipate the 24-h rotation of the Earth. In mammals, circadian integration of metabolic systems optimizes energy harvesting and utilization across the light/dark cycle. Disruption of clock genes has recently been linked to sleep disorders and to the development of cardiometabolic disease....
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