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The role of beta-cell dysfunction in early type 1 diabetes

29 Jun 2020

Abstract excerpt

PURPOSE OF REVIEW: Emerging data have suggested that β-cell dysfunction may exacerbate the development and progression of type 1 diabetes (T1D). In this review, we highlight clinical and preclinical studies suggesting a role for β-cell dysfunction during the evolution of T1D and suggest agents that may promote β-cell health in T1D. RECENT FINDINGS: Metabolic abnormalities exist years before development of...

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PMID: 32618633
DOI: 10.1097/med.0000000000000548

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