Article
β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment.
Diabetes care - 1 Jun 2014
Halban Philippe A, Polonsky Kenneth S, Bowden Donald W, Hawkins Meredith A, Ling Charlotte, Mather Kieren J, Powers Alvin C, Rhodes Christopher J, Sussel Lori, Weir Gordon C
Abstract excerpt
OBJECTIVE: This article examines the foundation of β-cell failure in type 2 diabetes (T2D) and suggests areas for future research on the underlying mechanisms that may lead to improved prevention and treatment. RESEARCH DESIGN AND METHODS: A group of experts participated in a conference on 14-16 October 2013 cosponsored by the Endocrine Society and the American Diabetes Association. A writing group prepared this...
Topics
- Congresses as Topic
- Diabetes Mellitus, Type 2
- Expert Testimony
- Genetic Predisposition to Disease
- Humans
- Insulin-Secreting Cells
- Signal Transduction