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Article

Chromosome X-wide association study identifies Loci for fasting insulin and height and evidence for incomplete dosage compensation.

PLoS genetics - 1 Feb 2014

Tukiainen Taru, Pirinen Matti, Sarin Antti-Pekka, Ladenvall Claes, Kettunen Johannes, Lehtimäki Terho, Lokki Marja-Liisa, Perola Markus, Sinisalo Juha, Vlachopoulou Efthymia, Eriksson Johan G, Groop Leif, Jula Antti, Järvelin Marjo-Riitta, Raitakari Olli T, Salomaa Veikko, Ripatti Samuli

Abstract excerpt

The X chromosome (chrX) represents one potential source for the "missing heritability" for complex phenotypes, which thus far has remained underanalyzed in genome-wide association studies (GWAS). Here we demonstrate the benefits of including chrX in GWAS by assessing the contribution of 404,862 c...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, X

Share to Dosage Compensation, Genetic

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Share to Fibroblast Growth Factors

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Source

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Identifiers

PMID: 24516404
DOI: 10.1371/journal.pgen.1004127
PMCID: PMC3916240

Genes

ATRX
FGF16
MAGT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24516404-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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