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Article

X-inactivation informs variance-based testing for X-linked association of a quantitative trait.

BMC genomics - 25 Mar 2015

Ma Li, Hoffman Gabriel, Keinan Alon

Abstract excerpt

BACKGROUND: The X chromosome plays an important role in human diseases and traits. However, few X-linked associations have been reported in genome-wide association studies, partly due to analytical complications and low statistical power. RESULTS: In this study, we propose tests of X-linked association that capitalize on variance heterogeneity caused by various factors, predominantly the process of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25880738
DOI: 10.1186/s12864-015-1463-y
PMCID: PMC4381508

Genes

AFF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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