Article
Identification of a novel Parkinson's disease locus via stratified genome-wide association study.
BMC genomics - 10 Feb 2014
Hill-Burns Erin M, Wissemann William T, Hamza Taye H, Factor Stewart A, Zabetian Cyrus P, Payami Haydeh
Abstract excerpt
BACKGROUND: Parkinson's disease (PD) is complex and heterogeneous. The numerous susceptibility loci that have been identified reaffirm the complexity of PD but do not fully explain it; e.g., it is not known if any given PD susceptibility gene is associated with all PD or a disease subtype. We also suspect that important disease genes may have escaped detection because of this heterogeneity. We used...
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