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Genome-wide association study using whole-genome sequencing identifies risk loci for Parkinson’s disease in Chinese population

9 Feb 2023

Abstract excerpt

Abstract Genome-wide association studies (GWASs) have identified numerous susceptibility loci for Parkinson’s disease (PD), but its genetic architecture remains underexplored in populations of non-European ancestry. To identify genetic variants associated with PD in the Chinese population, we performed a GWAS using whole-genome sequencing (WGS) in 1,972 cases and 2,478 controls, and a replication study in a total...

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PMID: 36759515
DOI: 10.1038/s41531-023-00456-6

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