Article
Association between HIV-1 tropism and CCR5 human haplotype E in a Caucasian population.
Journal of acquired immune deficiency syndromes (1999) - 1 Jul 2014
Huik Kristi, Avi Radko, Uibopuu Helen, Pauskar Merit, Margus Tõnu, Karki Tõnis, Krispin Tõnu, Kool Piret, Rüütel Kristi, Talu Ave, Abel-Ollo Katri, Uusküla Anneli, Carrillo Andrew, He Weijing, Ahuja Sunil K, Lutsar Irja
Abstract excerpt
BACKGROUND: The influence of the diversity of CCR5 on HIV susceptibility and disease progression has been clearly demonstrated but how the variability of this gene influences the HIV tropism is poorly understood. We investigated whether CCR5 haplotypes are associated with HIV tropism in a Caucasian population. METHODS: We evaluated 161 HIV-positive subjects in a cross-sectional study. CCR5 haplotypes were derived...
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