Article
Performance Evaluation of a Genotypic Tropism Test Using HIV-1 CRF01_AE Isolates in Japan.
Japanese journal of infectious diseases - 24 Jul 2018
Matsuda Masakazu, Louvel Séverine, Sugiura Wataru, Haas Alexandra, Pfeifer Nico, Yokomaku Yoshiyuki, Iwatani Yasumasa, Kaiser Rolf, Klimkait Thomas
Abstract excerpt
Geno2Pheno (coreceptor), a genotypic tropism test, demonstrates excellent agreement with the phenotypic tropism test for subtype B and some other subtypes. However, potential X4-overcalling for CRF01_AE might occur with the present version. To confirm X4 overcalling for AE and to optimize the algorithm for use with AE, we compared the tropism of 22 AE samples by both genotypic and phenotypic methods. The env V3...
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